How to clean Out of Office Rules using MFCMAPI - Slipstick Systems: http://www.slipstick.com/general/clean-out-of-office-rules-using-mfcmapi/
Exchange 2010 External Out of Office messages not going External: http://social.technet.microsoft.com/Forums/en-US/exchange2010/thread/87a815bb-c136-428c-8c69-dc3a69fdfd7f/
Clear OOF Rule in the mailbox:
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1. Turn off OOF on a problem user and close Outlook
2. Use MFCMapi tool to logon the problem user’s mailbox (by using Online Mode profile)
3. Expand Root Container->Top of Information Store
4. Right click Inbox folder and click Open Associated contents table
5. Delete following messages if exist:
a. Message class == IPM.Rule.Message
0x65EB001E == Microsoft Exchange OOF Assistant
0x65EC001E == Microsoft.Exchange.OOF.InternalSenders.Global
b. Message class == IPM.Note.Rules.OofTemplate.Microsoft
c. Message class == IPM.Rule.Message
0x65EB001E == MSFT:TDX OOF Rules
d. Message class == IPM.Rule.Message
0x65EB001E == Microsoft Exchange OOF Assistant
0x65EC001E == Microsoft.Exchange.OOF. AllExternalSenders.Global
e. Message class == IPM.Note.Rules.ExternalOOFTemplate.Microsoft
f. Message class == IPM.ExtendedRule.Message
0x65EB001E == Microsoft Exchange OOF Assistant
0x65EC001E == Microsoft.Exchange.OOF.KnownExternalSenders.Global
6. After that, please start Outlook and configure OOF for the user. Please check whether the issue persists.
New-MailboxRepairRequest: Exchange 2010 Help: http://technet.microsoft.com/en-us/library/ff625226(v=exchg.141).aspx
Out of Office not sending replies: http://exchangeserverpro.com/forums/exchange-server-2010/1551-out-office-not-sending-replies.html
Download MFCMapi from Official Microsoft Download Center: http://www.microsoft.com/en-us/download/details.aspx?id=2953
Microsoft Exchange Server MAPI Editor: http://technet.microsoft.com/en-us/library/bb508857(EXCHG.65).aspx